ObjectivesThis study aimed to explore the relationship between 18 single nucleotide polymorphisms (SNPs) and Alzheimer’s disease (AD) within the southern Chinese population.MethodsA total of 420 participants, consisting of 215 AD patients and 205 sex- and age-matched controls, were recruited. The SNaPshot technique and polymer chain reaction (PCR) were used to detect the 18 SNPs. Combined […]

Naturalistic observations show that decisions to avoid or escape predators occur at different spatiotemporal scales and that they are supported by different computations and neural circuits. At their extremes, proximal threats are addressed by a limited repertoire of reflexive and myopic actions, reflecting reduced decision and state spaces and model-free (MF) architectures. Conversely, distal threats […]

Theta frequency (4–8 Hz) fluctuations of the local field potential have long been implicated in learning and memory. Human studies of episodic memory, however, have provided mixed evidence for theta’s role in successful learning and remembering. Re-evaluating these conflicting findings leads us to conclude that: (i) successful memory is associated both with increased narrow-band theta […]