Cognitive Science

The latest breakthroughs, innovations, and cool happenings at the cutting edge of the world of cognitive science. Updated daily.

Insulin Resistance Predicts Postoperative Cognitive Dysfunction in Elderly Gastrointestinal Patients

BACKGROUND: Aging population undergoing surgery are at risk of postoperative cognitive dysfunction (POCD). Exploring effective and reliable early predictor of POCD is essential to identify high-risk patients and make prospective decisions. The purpose of this study was to examine whether preoperative insulin resistance, is an independent predictor of POCD. METHODS: A total of 124 aged […]

Published on August 9, 2019

The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

Mild cognitive impairment (MCI) is a transitional state between the cognitive changes in normal aging and Alzheimer’s disease (AD), which induces abnormalities in specific brain regions. Previous studies showed that paired helical filaments Tau (PHF-Tau) protein is a potential pathogenic protein which may cause abnormal brain function and structure in MCI and AD patients. However, […]

Published on August 9, 2019

Resting State Networks in the TgF344-AD Rat Model of Alzheimer’s Disease Are Altered From Early Stages

A better and non-invasive characterization of the preclinical phases of Alzheimer’s disease (AD) is important to advance its diagnosis and obtain more effective benefits from potential treatments. The TgF344-AD rat model has been well characterized and shows molecular, behavioral and brain connectivity alterations that resemble the silent period of the pathology. Our aim was to […]

Published on August 9, 2019