In experimental psychology, subjects are confronted with computer-based experimental paradigms. Creating such paradigms can require quite an effort. PyParadigm is a newly developed Python library to ease the development of such paradigms by employing a declarative approach to build user interfaces (UIs). This approach is a highly code-efficient alternative to currently available libraries. Although PyParadigm […]

The identification of biomarkers of Alzheimer’s disease (AD) is an important and urgent area of study, not only to aid in the early diagnosis of AD, but also to evaluate potentially new anti-AD drugs. The aim of this study was to explore cofilin 2 in serum as a novel biomarker for AD. The upregulation was […]

Soluble amyloid-β (Aβ) oligomers have been shown to induce oxidative stress, synaptic dysfunction and memory deficits which have been reported in Alzheimer’s disease (AD). Administration of γ-glutamylcysteine (GGC), a precursor to glutathione (GSH) can replenish depleted GSH levels, by circumventing the regulation of GSH biosynthesis and providing the limiting substrate. In this study, we examined […]