Amyloid-β (Aβ) deposits and some proteins play some essential roles in AD pathogenesis. Amide proton transfer (APT) imaging as an indicator of tissue protein has shown promise for AD diseases. In this study, we chose 20 AD model rats as the experimental group and 20 sham-operated rats as the control group. They were firstly underwent […]

Deteriorated speech comprehension is a common manifestation of the age-related decline of auditory functions (presbycusis). It could be assumed that when presbycusis is accompanied by tinnitus, general hearing functions, and particularly comprehension of speech in quiet and speech in noise, will be significantly affected. In this study, speech comprehension ability and other parameters of auditory […]

After experiences are encoded into memory, post-encoding reactivation mechanisms have been proposed to mediate long-term memory stabilization and transformation. Spontaneous reactivation of hippocampal representations, together with hippocampal–cortical interactions, are leading candidate mechanisms for promoting systems-level memory strengthening and reorganization. While the replay of spatial representations has been extensively studied in rodents, here we review recent […]