Neuroimaging studies suggest disrupted connections of the brain white matter (WM) network in bipolar disorder (BD). A group of highly interconnected high-density structures, termed the ‘rich club,’ represents an important network for brain functioning. Recent works have revealed abnormal rich club organization in brain networks in BD. However, little is known regarding changes in the […]

This review aimed to systematically summarize the possible neural correlates of cognitive reserve thus giving an insight into prospective biomarkers for the concept. A total of 44 studies were analyzed following PRISMA guidelines and four studies were included in the further analysis. The results indicated a relationship between P3b waveform and cognitive reserve, while more […]

Background: Accumulating evidence has demonstrated a significant association between microglia-driven inflammation in the brain and neurodegenerative dementia. We previously showed a significant decline in CISD2 expression in mice models with advanced age. Moreover, we observed that the knockdown of CISD2 led to remarkable inflammation and mitochondrial dysfunction in neural cells. In the present study, we […]