The study’s note that standard hormone therapy did not reverse grey matter changes raises important questions about which interventions, if any, can protect cognitive and emotional function. Researchers observed slower reaction-time decline with hormone use, which suggests there could be targeted benefits even if broad structural effects persist. Thinking about timing, individual risk, and nonhormonal strategies becomes essential for anyone planning long-term brain health.

If menopause represents a turning point for brain aging, it should be part of discussions about prevention, monitoring, and inclusive care. Knowing where the gaps in evidence remain invites new studies and better clinical guidance. Follow the link to read the full article and learn how these findings might reshape our approach to supporting cognitive resilience and mental health during midlife and beyond.
A major study suggests menopause is linked to changes in brain structure, mental health, and sleep. Brain scans revealed grey matter loss in areas tied to memory and emotional regulation, while many women reported increased anxiety, depression, and fatigue. Hormone therapy did not reverse these effects, though it may slow age-related declines in reaction speed. Researchers say menopause could represent an important turning point for brain health.