The trials due next month will offer unusually strong evidence because of their scale and design. Large, well-controlled studies give clearer answers than small experiments, so these results could shift how scientists think about repurposing metabolic drugs for brain conditions. For clinicians and families, the findings could influence care decisions and what researchers prioritize next, from new drug targets to the kinds of patients chosen for future studies.

If the trials show a meaningful effect, the impact on human potential could be wide. Slowing cognitive decline would change expectations for aging, independence, and support systems. If the drugs don’t help, the data will still teach us which biological pathways matter and which do not. Either outcome will steer research and policy in ways that touch inclusion, caregiving, and how society supports people living with dementia.

Studies from Novo Nordisk due early next month will give the strongest indication yet of whether blockbuster GLP-1 drugs – a class being used by millions for diabetes and weight loss – can slow progress of Alzheimer’s disease. Two trials, described by Novo as a “lottery…

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