Negative results like this reshape research priorities. Funders, labs, and families all pay attention when a high-profile candidate fails, because those data steer where effort and money go next. That process can speed clearer answers about which biological pathways are most promising, which patient groups might benefit, and how to design smarter trials that learn more from every participant.

For anyone interested in human potential, these findings highlight a larger truth about progress in medicine: advances arrive through many fits and starts, and each outcome teaches something useful. Read the full report to explore how this setback might reframe future dementia research, who could be affected, and what new strategies researchers are pursuing to preserve cognition and quality of life.

Novo Nordisk’s closely-watched Alzheimer’s trials of an older oral version of its semaglutide drug failed to help slow the progression of the brain-wasting disease, the firm said on Monday, a blow to the obesity drug giant that sent its shares sliding. The trials, which Novo…

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