How dopamine helps us learn to avoid bad outcomes

Published on April 22, 2025

Dopamine is the brain’s motivational spark, driving us to chase what feels good, say scrolling another reel on social media, and steer clear of what doesn’t, like touching a hot stove. But scientists haven’t fully understood how dopamine helps us learn to avoid bad outcomes — until now. A new study shows that dopamine signals in two key brain areas involved in motivation and learning respond differently to negative experiences, helping the brain adapt based on whether a situation is predictable or controllable. While previous research has shown that dopamine can respond to negative experiences, this is the first study to track how those signals evolve over time as animals move from novices to experts in avoiding them.

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