Unveiling Changes in Brain Structure and Function in Subjective Cognitive Decline

Published on September 18, 2023

The human brain is like a complex puzzle, and understanding its intricate inner workings is crucial to unraveling the mysteries of diseases like Alzheimer’s. In this mini-review, we delve into the exciting world of multimodal magnetic resonance imaging (MRI) and how it sheds light on subjective cognitive decline (SCD), the early stage of Alzheimer’s disease. Like detectives exploring clues at a crime scene, researchers have utilized advanced MRI techniques such as structural MRI (sMRI), diffusion tensor imaging (DTI), and functional MRI (fMRI) to examine the brains of individuals with SCD. By analyzing brain structures and functions, we hope to uncover valuable insights that can aid in the early diagnosis and targeted treatment of SCD, potentially delaying the onset of Alzheimer’s. If you’re curious about the fascinating discoveries made through multimodal MRI research on SCD, grab your scientific magnifying glass and dive into the full article!

Subjective cognitive decline (SCD) is the initial stage of Alzheimer’s disease (AD). Early identification of SCD and its risk factors is of great importance for targeted interventions and for delaying the onset of AD. We reviewed the relevant literature on structural magnetic resonance imaging (sMRI), diffusion tensor imaging (DTI), functional magnetic resonance imaging (fMRI), and other techniques regarding SCD research in recent years. This study applied sMRI and fMRI techniques to explore abnormal brain structures and functions, which may help provide a basis for SCD diagnosis.

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