COVID-19’s Impact on Brain Function and Health

Published on August 31, 2023

The effects of COVID-19 on the brain are like wearing a blindfold while solving a puzzle. Just as the blindfold limits our ability to see and solve the puzzle, COVID-19 can impair our cognitive function and mental health. Even after recovering from the virus, some people experience lingering symptoms that affect their cognition and overall brain health. Research has shown that these symptoms can persist for months, indicating a long-lasting impact. Studies using neuroimaging techniques have provided insight into the nature of these symptoms. Interestingly, cognitive deficits can be present in individuals without any visible brain abnormalities or objective cognitive impairments. This suggests that there may be underlying mechanisms at play that we are yet to fully understand. By delving into the evidence surrounding symptoms, cognitive deficits, and neuroimaging, scientists hope to uncover the complex picture of how COVID-19 affects our brains.

COVID-19 is associated with a range of neurological, cognitive, and mental health symptoms both acutely and chronically that can persist for many months after infection in people with long-COVID syndrome. Investigations of cognitive function and neuroimaging have begun to elucidate the nature of some of these symptoms. They reveal that, although cognitive deficits may be related to brain imaging abnormalities in some people, symptoms can also occur in the absence of objective cognitive deficits or neuroimaging changes. Furthermore, cognitive impairment may be detected even in asymptomatic individuals. We consider the evidence regarding symptoms, cognitive deficits, and neuroimaging, as well as their possible underlying mechanisms.

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