Imagine unraveling a global treasure map that leads you to the most sought-after artifacts in the world. Well, scientists have done something similar with Parkinson’s disease and phenolic compounds! In this groundbreaking study, researchers scoured through a vast collection of scientific articles to identify and analyze the top 100 most cited papers on the topic. Using fancy tools like MapChart and VOSviewer software, they created visual networks showcasing the worldwide impact of this research. What did they discover? The oldest article was also the most cited, proving that its findings have withstood the test of time. Asia and China took the lead in contributing to this body of knowledge, with a staggering number of publications. Interestingly, in vitro studies emerged as the most popular experimental design, highlighting the importance of fundamental research in unraveling the mysteries of PD and PCs. As for the specific compounds under investigation, epigallocatechin stole the limelight, captivating scientists with its potential therapeutic benefits for PD. And while oxidative stress took center stage as the most studied therapeutic target, there’s still much more to explore. By delving into these pioneering studies, we can gain valuable insights and pave the way for future clinical investigations to deepen our understanding of this complex association.
ObjectiveThe aim of this study was to identify and characterize the 100 most cited articles on Parkinson’s disease (PD) and phenolic compounds (PCs).MethodsArticles were selected in the Web of Science Core Collection up to June 2022 based on predetermined inclusion criteria, and the following bibliometric parameters were extracted: the number of citations, title, keywords, authors, year, study design, tested PC and therapeutic target. MapChart was used to create worldwide networks, and VOSviewer software was used to create bibliometric networks. Descriptive statistical analysis was used to identify the most researched PCs and therapeutic targets in PD.ResultsThe most cited article was also the oldest. The most recent article was published in 2020. Asia and China were the continent and the country with the most articles in the list (55 and 29%, respectively). In vitro studies were the most common experimental designs among the 100 most cited articles (46%). The most evaluated PC was epigallocatechin. Oxidative stress was the most studied therapeutic target.ConclusionDespite the demonstrations in laboratorial studies, the results obtained point to the need for clinical studies to better elucidate this association.
Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
Armed with a Master of Science degree and a Ph.D. in his field, Dr. Lowemann has consistently been at the forefront of research and innovation, delving into ways to optimize human performance, cognition, and overall well-being. His work at the Institute revolves around a profound commitment to harnessing cutting-edge science and technology to help individuals lead more fulfilling and intelligent lives.
Dr. Lowemann’s influence extends to the educational platform BetterSmarter.me, where he shares his insights, findings, and personal development strategies with a broader audience. His ongoing mission is shaping the way we perceive and leverage the vast capacities of the human mind, offering invaluable contributions to society’s overall success and collective well-being.