ASD is a heterogeneous neurodevelopmental condition of unknown etiology. It impacts a wide range of functions, from social and communicative faculties [1] to motor behaviors [2] and sensory processing [3]. Similarly, a wide range of genetic [4] and environmental [5] factors have been linked to the disorder. As such, there are a great number of theories of ASD, and these are as diverse as the condition itself. Some emphasize psychological descriptions such as weak central coherence (see Glossary) [6] and theory of mind [7], or focus on brainwide [8] or microcircuit [9] connectivity patterns, and still others highlight particular neurotransmitters [10] or genetic mutations [11–13].

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