A whiff of hope: Essential oils from herbs show promise in treating cognitive impairment

Published on March 16, 2023

Cognitive impairment, particularly in the form of Alzheimer’s disease, is becoming a more prevalent health issue. Unfortunately, there are currently no go-to treatments for halting or reversing the disease. But fear not, because researchers are exploring the potential of essential oils derived from natural herbs to tackle this problem! Essential oils have a wide range of chemical components that make them effective, safe, and easy to use. In this review, the authors examine how essential oils can improve cognition by reducing neurotoxicity, combating oxidative stress, modulating the cholinergic system, and mitigating brain inflammation. They also delve into the advantages of combining essential oils with aromatherapy. This comprehensive review aims to provide a solid scientific foundation and fresh insights into using natural essential oils as a therapeutic strategy for cognitive impairment. So take a deep breath, inhale the aroma of science, and explore the exciting potential of herbal medicine!

Cognitive impairment (CI), mainly Alzheimer’s disease (AD), continues to increase in prevalence and is emerging as one of the major health problems in society. However, until now, there are no first-line therapeutic agents for the allopathic treatment or reversal of the disease course. Therefore, the development of therapeutic modalities or drugs that are effective, easy to use, and suitable for long-term administration is important for the treatment of CI such as AD. Essential oils (EOs) extracted from natural herbs have a wide range of pharmacological components, low toxicity, and wide sources, In this review, we list the history of using volatile oils against cognitive disorders in several countries, summarize EOs and monomeric components with cognitive improvement effects, and find that they mainly act by attenuating the neurotoxicity of amyloid beta, anti-oxidative stress, modulating the central cholinergic system, and improving microglia-mediated neuroinflammation. And combined with aromatherapy, the unique advantages and potential of natural EOs in the treatment of AD and other disorders were discussed. This review hopes to provide scientific basis and new ideas for the development and application of natural medicine EOs in the treatment of CI.

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