Microprotein increases appetite in mice

Published on January 3, 2023

Imagine a pantry filled with countless secret snacks that nobody knew existed! Well, something like that was found in both brown and white fat. Scientists recently uncovered thousands of these sneaky, tiny molecules, known as microproteins. One of them, called Gm8773, has an interesting superpower — it can make mice want to eat more! This discovery could potentially be used to design a special therapy for people who need to gain weight under specific circumstances, like when going through cancer treatment like chemotherapy. By understanding how this microprotein works in mice, scientists hope to develop a similar approach for human treatment. Further research is needed to determine if this trick works for humans too. Exciting times are ahead in the world of weight management research! So, if you’re curious to learn more about these tiny molecules that can influence our cravings and hunger, check out the original article!

Scientists have discovered that both brown and white fat is filled with thousands of previously unknown microproteins, and show that one of these microproteins, called Gm8773, can increase appetite in mice. These findings could lead to the development of a therapeutic to help people gain weight in certain disease situations, such as during chemotherapy for cancer.

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