Developmental Changes in Brain Systems Support Executive Function

Published on November 25, 2022

Imagine the brain as a complex organization with different departments. In this perspective, scientists have discovered that as we grow, our executive function abilities improve thanks to changes in the brain’s functional systems. These systems are like different divisions within an organization, each responsible for specific tasks. The researchers found that these functional systems are arranged hierarchically along a sensorimotor-association axis of cortical organization, similar to how departments are organized within a company. The study also revealed that as we develop, these functional systems undergo changes: the systems at the associative end become more specialized in their functions, while those in the middle become more integrated in their operations. This intricate balance between specialization and integration supports the improvement of executive function in youth. By understanding the hierarchical nature of brain organization and its impact on executive function, we can potentially develop interventions to enhance these cognitive abilities. To delve deeper into this fascinating research, check out the full article.

In this perspective, we describe how developmental improvements in youth executive function (EF) are supported by hierarchically organized maturational changes in functional brain systems. We first highlight evidence that functional brain systems are embedded within a hierarchical sensorimotor-association axis of cortical organization. We then review data showing that functional system developmental profiles vary along this axis: systems near the associative end become more functionally segregated, while those in the middle become more integrative.

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