Motoric Cognitive Risk Syndrome Linked to Future Disability: 7-Year Study

Published on September 8, 2022

Imagine if I told you that slow walking and feeling forgetful could be signs of something more serious? Well, a group of scientists conducted a fascinating study on what they called Motoric Cognitive Risk Syndrome (MCR). They wanted to see if MCR could predict future disability in older adults. And guess what? They found a strong association between MCR and incident disability after following the participants for 7 years. MCR is like a warning sign, telling us that trouble might be brewing. It’s kind of like when your car engine makes a strange noise and you know it’s time to take it to the mechanic. In this case, MCR is telling us that the brain and body may not be working as well as they should be. So, it’s really important to identify MCR early on so that we can take steps to prevent or delay disability. If we catch MCR early, we can think of it like an early warning system for potential future problems. But there’s still more research to be done! To learn more about this exciting study, check out the original research article.

BackgroundThough motoric cognitive risk syndrome (MCR) share risk factors with disability, whether it predict disability remains understudied.ObjectivesThis study aims to examine the association between MCR and incident disability.DesignLongitudinal study.MethodsMCR was defined as subjective cognitive complaints and objective slow gait speed. Two subtypes of MCR were defined by whether memory impairment (MI) was also present, MCR-MI and MCR-non-MI. Incident activities of daily living (ADL) disability and instrumental activities of daily living (IADL) disability were outcome measures. Multiple logistic regression analysis was used to assess the independent effect of MCR at baseline on the odds of ADL/IADL disability at a 7 year follow-up.ResultsAmong the subjects who were not disabled at baseline and followed for 7 years, 34.66% reported incident ADL disability, and 31.64% reported incident IADL disability. Compared with participants without MCR at baseline, those with MCR had 58% increased odds of incident ADL disability (OR=1.58, 95% CI: 1.19–2.09) and 46% increased odds of incident IADL disability (OR=1.46, 95% CI: 1.13–1.88) after 7 years. MCR-non-MI was associated with a 56.63% increased risk of ADL disability and a 34.73% increased risk of IADL disability. MCR-MI was associated with an even higher risk of IADL disability (OR = 2.14, 95% CI: 1.18–3.88).ConclusionsMCR is an independent risk factor for both incident ADL and IADL disability. MCR-MI predicts a higher risk for disability than MCR-non-MI. Early identification of MCR among older adult is recommended and may decrease future risk of disability.

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