vol2Brain: A New Online Pipeline for Whole Brain MRI Analysis

Published on May 24, 2022

Imagine you’re building a complex puzzle. Each piece represents a different part of the brain, and putting them together accurately is crucial for understanding how the brain works. Well, scientists have developed an incredible new tool called vol2Brain that takes brain MRI scans and neatly labels over 100 brain regions in just a few minutes! It’s like having a team of expert puzzle solvers working at lightning speed. What’s even more amazing is that vol2Brain can handle tricky situations, like white matter lesions, making it an invaluable resource for both research and clinical settings. This is a big leap forward from previous methods that couldn’t capture such detailed information. With vol2Brain, scientists can finally analyze the brain at a much deeper level, unlocking insights into brain anatomy and function. To make this breakthrough accessible to everyone, the volBrain platform allows users worldwide to experience the power of vol2Brain firsthand. So, if you’re curious about how your brain pieces fit together, check out volBrain and start exploring the wonders of whole brain analysis!

Automatic and reliable quantitative tools for MR brain image analysis are a very valuable resource for both clinical and research environments. In the past few years, this field has experienced many advances with successful techniques based on label fusion and more recently deep learning. However, few of them have been specifically designed to provide a dense anatomical labeling at the multiscale level and to deal with brain anatomical alterations such as white matter lesions (WML). In this work, we present a fully automatic pipeline (vol2Brain) for whole brain segmentation and analysis, which densely labels (N > 100) the brain while being robust to the presence of WML. This new pipeline is an evolution of our previous volBrain pipeline that extends significantly the number of regions that can be analyzed. Our proposed method is based on a fast and multiscale multi-atlas label fusion technology with systematic error correction able to provide accurate volumetric information in a few minutes. We have deployed our new pipeline within our platform volBrain (www.volbrain.upv.es), which has been already demonstrated to be an efficient and effective way to share our technology with the users worldwide.

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