Recurring Intracerebral Hemorrhage: A Different Beast!

Published on April 14, 2022

Imagine you’re in a wildlife safari, observing animals in their natural habitat. Among the animals, you notice a distinct group that stands out – they’re older, have more health issues, and have been through tough experiences before. These animals are like the recurrent intracerebral hemorrhage (ICH) patients in this study! Researchers studied over 4,000 ICH patients and compared those who had experienced a recurrence to those experiencing ICH for the first time. They found that recurrent ICH patients were older and had a higher likelihood of conditions like ischemic heart disease, ischemic stroke, hypertension, and hyperlipidemia. They also received more antihypertensive therapy and had different clinical characteristics upon admission. The study showed that recurrent ICH was an independent risk factor for function dependence after three months. Fascinatingly, these findings suggest that recurring ICH is like encountering experienced animals in the wild – they have different patterns of behavior and pose unique challenges. To dig deeper into this research, check out the full article!

This study aimed to compare clinical and prognostic characteristics between recurrent and first-ever ICH. Four thousand twelve patients entered the study, and 64% of them were male. The median age is 62 years (interquartile range, 55–71). Among them, 3,750 (93.5%) patients had no experience of previous ICH, and 262 (6.5%) patients were considered as recurrent ICH. We compared demographic data, baseline clinical characteristics, imaging information, hematological parameters, and clinical outcomes between recurrent and first-ever ICH. We found that recurrent ICH was significantly associated with older age, more frequent history of ischemic heart disease, ischemic stroke, hypertension, and hyperlipidemia, while patients with recurrent ICH had previously received more antihypertensive therapy, and showed lower admission blood pressure (median, 160 vs. 167 mmHg) and higher baseline of National Institute of Health stroke scale (NIHSS) score (median, 10 vs. 9). We also demonstrated that recurrent ICH was an independent risk factor of 3-month function dependence after adjusting for many potentially competitive risk factors.

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