The Best Laid Plans: Computational Principles of Anterior Cingulate Cortex

Published on February 14, 2021

Despite continual debate for the past 30 years about the function of anterior cingulate cortex (ACC), its key contribution to neurocognition remains unknown. However, recent computational modeling work has provided insight into this question. Here we review computational models that illustrate three core principles of ACC function, related to hierarchy, world models, and cost. We also discuss four constraints on the neural implementation of these principles, related to modularity, binding, encoding, and learning and regulation.

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