Early detection of mild cognitive impairment (MCI) has become a priority in Alzheimer’s disease (AD) research, as it is a transitional phase between normal aging and dementia. However, information on MCI and AD is scattered across different formats and standards generated by different technologies, making it difficult to work with them manually. Ontologies have emerged […]

Cognitive control and decision-making rely on the interplay of medial and lateral prefrontal cortex (mPFC/lPFC), particularly for circumstances in which correct behavior requires integrating and selecting among multiple sources of interrelated information. While the interaction between mPFC and lPFC is generally acknowledged as a crucial circuit in adaptive behavior, the nature of this interaction remains […]

Background: More people with cognitive dysfunction and dementia also fall into the category of high vascular risk, for which aspirin is one of the most frequently used drugs. However, previous studies reporting that aspirin buffers against mild cognitive decline (MCI) and dementia remain controversial. We thus conducted an updated systematic review and meta-analysis to evaluate […]