Month: December 2019

Evaluation of Six Phase Encoding Based Susceptibility Distortion Correction Methods for Diffusion MRI

Purpose: Susceptibility distortions impact diffusion MRI data analysis and is typically corrected during preprocessing. Correction strategies involve three classes of methods: registration to a structural image, the use of a fieldmap, or the use of images acquired with opposing phase encoding directions. It has been demonstrated that phase encoding based methods outperform the other two […]

Published on December 5, 2019

Passing the Message: Representation Transfer in Modular Balanced Networks

Neurobiological systems rely on hierarchical and modular architectures to carry out intricate computations using minimal resources. A prerequisite for such systems to operate adequately is the capability to reliably and efficiently transfer information across multiple modules. Here, we study the features enabling a robust transfer of stimulus representations in modular networks of spiking neurons, tuned […]

Published on December 5, 2019

Predictive Value of Routine Peripheral Blood Biomarkers in Alzheimer’s Disease

BackgroundBiomarker screening is of major significance for the early diagnosis and prevention of Alzheimer’s disease (AD). Routine peripheral blood parameters are easy to collect and detect, making them ideal potential biomarkers. Thus, we aimed to evaluate the parameters from routine blood as potential biomarkers for AD.MethodsWe enrolled 56 AD patients, 57 mild cognitive impairment (MCI) […]

Published on December 5, 2019