Imagine the striatum (a brain region) as a bustling city. The mayor of this city is called Rhes, who has an important job in maintaining order and balance. But in Huntington’s disease (HD), trouble arises when mutant huntingtin (a harmful protein) starts piling up in the city. Our study shows that when we knock down […]
Published on August 10, 2023
Neurological disorders have a puzzling connection to the aging process within our brain’s synapses. Like a delicate ballet, molecular and cellular mechanisms are at play, determining the fate of these vital connections. Scientists are uncovering emerging pathways that shed light on how synaptopathies develop as we age. Proteins, gene expression, and intricate signaling networks all […]
Published on August 10, 2023
Our body’s sense of balance relies on the vestibular system, which is responsible for sensing motion and spatial orientation. As we age, our balance tends to decline, leading to a higher risk of falls. Researchers studied how different elements of the vestibular system contribute to this age-related decline in balance. By measuring vestibular perceptual thresholds […]
Published on August 10, 2023