Imagine being a treasure hunter, searching for the rarest and most precious gems hidden in the vast depths of the ocean. Just like those gems, there is a wealth of neuroimaging data waiting to be discovered in the depths of scientific literature. With the NeuroBridge prototype, scientists have developed a powerful platform that can uncover […]
Published on August 31, 2023
IntroductionMetabolomics technology facilitates studying associations between small molecules and disease processes. Correlating metabolites in cerebrospinal fluid (CSF) with Alzheimer’s disease (AD) CSF biomarkers may elucidate additional changes that are associated with early AD pathology and enhance our knowledge of the disease.MethodsThe relative abundance of untargeted metabolites was assessed in 161 individuals from the Wisconsin Registry […]
Published on August 30, 2023
IntroductionFrailty is a geriatric syndrome frequently associated with executive dysfunction and white matter hyperintensities (WMH). But the relation between executive dysfunction and brain changes is poorly understood in frail subjects. Our hypothesis is that frontal-WMH mediates the association between frailty and executive dysfunction.MethodsA convenience sample of 113 subjects older than 65 years without dementia was […]
Published on August 30, 2023