Huntington’s disease (HD) is a neurodegenerative disease characterized by movement and cognitive dysfunction. HD is caused by a CAG expansion in exon 1 of the HTT gene that leads to a polyglutamine (PQ) repeat in the huntingtin protein, which aggregates in the brain and periphery. Previously, we used Drosophila models to determine that Htt-PQ aggregation […]
Published on September 26, 2023
Imagine the hypothalamus as a master switchboard in your brain, controlling not only basic functions like hunger and thirst, but also determining what you learn and remember. While it was previously believed that the lateral hypothalamus only regulated feeding behaviors, recent research has shown that it plays a critical role in learning about food-related cues. […]
Published on September 26, 2023
Parkinson’s disease is like a complex dance, with each patient taking their own unique steps. A new study followed a multiethnic, multisite cohort of PD patients to understand the progression and outcomes of the disease. By using trajectory modeling, researchers identified three distinct groups based on disease progression: a slow and benign group, a moderate […]
Published on September 26, 2023