Cognitive Science

The latest breakthroughs, innovations, and cool happenings at the cutting edge of the world of cognitive science. Updated daily.

Cognitive Profiles of Aging in Multiple Sclerosis

Background. Increasingly favorable mortality prognosis in multiple sclerosis (MS) raises questions regarding MS-specific cognitive aging and the presence of comorbidities such as Alzheimer’s disease (AD). Objective. To assess elderly with MS (EwMS) and age-matched healthy controls (HCs) using both MS- and AD-specific psychometrics. Methods. EwMS (n=104) and 56 HCs were assessed on a broad spectrum […]

Published on May 11, 2019

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

Alzheimer’s disease (AD) is reportedly associated with the accumulation of calcium ions (Ca2+), and this accumulation is responsible for the phosphorylation of tau. Although several lines of evidence demonstrate the above phenomenon, the inherent mechanisms remain unknown. Using APP/PS1 Tg mice and neuroblastoma (N)2a cells as in vivo and in vitro experimental models, we observed […]

Published on May 10, 2019