Cellular senescence is a biological aging hallmark that plays a key role in the development of neurodegenerative diseases. Clinical trials are currently underway to evaluate the effectiveness of senotherapies for these diseases. However, the impact of senescence on brain aging and cognitive decline in the absence of neurodegeneration remains uncertain. Moreover, patient populations like cancer […]

BackgroundVisuospatial memory impairment is a common symptom of Alzheimer’s disease; however, conventional visuospatial memory tests are insufficient to fully reflect visuospatial memory impairment in daily life.MethodsTo address patients’ difficulties in locating and recalling misplaced objects, we introduced a novel visuospatial memory test, the Hidden Objects Test (HOT), conducted in a virtual environment. We categorized HOT […]

Abstract People exhibit conflicting intuitions concerning the mind/body links. Here, I explore a novel explanation for these inconsistencies: Dualism is a violable constraint that interacts with Essentialism. Two experiments probe these interactions. In Experiment 1, participants evaluated the emergence of psychological traits in either a replica of one’s body, or in the afterlife—after the body’s […]