Previous studies investigating working memory performance in patients with mild cognitive impairment (MCI) have mainly focused on the neural mechanisms of alterations in activation. To date, very few studies have investigated background network alterations in the working memory state. Therefore, the present study investigated the static and temporal dynamic changes in the background network in […]
Published on June 28, 2019
White matter hyperintensities (WMH) appear as regions of abnormally high signal intensity on T2-weighted magnetic resonance image (MRI) sequences. In particular, WMH have been noteworthy in age-related neuroscience for being a crucial biomarker for all types of dementia and brain aging processes. The automatic WMH segmentation is challenging because of their variable intensity range, size […]
Published on June 28, 2019
Cognitive neuroscience has traditionally focused on simple tasks, presented sparsely and using abstract stimuli. While this approach has yielded fundamental insights into functional specialisation in the brain, its ecological validity remains uncertain. Do these tasks capture how brains function ‘in the wild’, where stimuli are dynamic, multimodal, and crowded? Ecologically valid paradigms that approximate real […]
Published on June 28, 2019