Since first described in the early 1900s, Alzheimer’s disease (AD) has risen exponentially in prevalence and concern. Research still drives to understand the etiology and pathogenesis of this disease and what risk factors can attribute to AD. With a majority of AD cases being of sporadic origin, the increasing exponential growth of an aged population […]

Abstract Intonation plays an integral role in comprehending spoken language. Listeners can rapidly integrate intonational information to predictively map a given pitch accent onto the speaker’s likely referential intentions. We use mouse tracking to investigate two questions: (a) how listeners draw predictive inferences based on information from intonation? and (b) how listeners adapt their online […]

The discouraging results with therapies for Alzheimer´s disease (AD) in clinical trials, highlights the urgent need to adopt new approaches. Like other complex diseases, it is becoming clear that AD therapies should focus on the simultaneous modulation of several targets implicated in the disease. Recently, using reference compounds and the first-in class CM-414, we demonstrated […]