Aging is associated with declines in motor and somatosensory function. Some of these motor declines have been linked to age-related reductions in inhibitory function. Here we examined whether tactile surround inhibition also changes with age, and whether these changes are associated with those in the motor domain. We tested a group of 56 participants spanning […]

During the last decade several papers reported a relationship between advanced age and changes in the integrity of the blood-brain barrier. These alterations manifested not only in the morphology and structure of the cerebral microvessels but also in the expression and function of the transporter proteins in the apical and basolateral surface of the capillary […]

The human ability to anticipate the consequences that result from action is an essential building block for cognitive, emotional, and social functioning. A dominant view is that this faculty is based on motor predictions, in which a forward model uses a copy of the motor command to predict imminent sensory action-consequences. Although this account was […]