Microtubules (MTs) play a fundamental role in many vital processes such as cell division and neuronal activity. They are key structural and functional elements in axons, supporting neurite differentiation and growth, as well as transport along the axons by the motor proteins, which use MTs as support tracks. Tau is a stabilizing MT associated protein, […]

Although the mechanisms of Alzheimer’s disease are diverse and unclear, the past 20 years have witnessed the unprecedented development of the AD inflammation theory. As a key inflammatory receptor family, the C-C chemokine receptor family is a remarkable participant in the cause of Alzheimer’s disease; of this family, CCR5 is the most widely studied. CCR5 […]

Background and Purpose: Ambulatory blood pressure variability (ABPV), ambulatory blood pressure (ABP) and carotid intima-media thickness (IMT) are closely associated with white matter hyperintensities (WMH), few studies focused on establishing effective models based on ABP, ABPV and IMT to predict the WMH burden, we aimed to evaluate the value of predictive model based on metrics […]