Cognitive Science

The latest breakthroughs, innovations, and cool happenings at the cutting edge of the world of cognitive science. Updated daily.

Cofilin 2 in Serum as a Novel Biomarker for Alzheimer’s Disease in Han Chinese

The identification of biomarkers of Alzheimer’s disease (AD) is an important and urgent area of study, not only to aid in the early diagnosis of AD, but also to evaluate potentially new anti-AD drugs. The aim of this study was to explore cofilin 2 in serum as a novel biomarker for AD. The upregulation was […]

Published on August 10, 2019

The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes

Soluble amyloid-β (Aβ) oligomers have been shown to induce oxidative stress, synaptic dysfunction and memory deficits which have been reported in Alzheimer’s disease (AD). Administration of γ-glutamylcysteine (GGC), a precursor to glutathione (GSH) can replenish depleted GSH levels, by circumventing the regulation of GSH biosynthesis and providing the limiting substrate. In this study, we examined […]

Published on August 9, 2019

Insulin Resistance Predicts Postoperative Cognitive Dysfunction in Elderly Gastrointestinal Patients

BACKGROUND: Aging population undergoing surgery are at risk of postoperative cognitive dysfunction (POCD). Exploring effective and reliable early predictor of POCD is essential to identify high-risk patients and make prospective decisions. The purpose of this study was to examine whether preoperative insulin resistance, is an independent predictor of POCD. METHODS: A total of 124 aged […]

Published on August 9, 2019