Aging is a major risk factor for cerebrovascular disease; however, the molecular mechanisms of cerebrovascular aging remain to be clarified. The aim of this study was to reveal the molecular signaling pathways involved in cerebrovascular aging. This study used high-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with quantitative 6-plex tandem mass […]
Published on October 23, 2019
The somatic nervous system of the nematode worm Caenorhabditis elegans is a model for understanding the physical characteristics of the neurons and their interconnections. Its neurons show high variation in morphological attributes. This study investigates the relationship of neuronal morphology to the number of synapses per neuron. Morphology is also examined for any detectable association […]
Published on October 22, 2019
Objectives: To characterize gait disorders in patients with amnestic mild cognitive impairment (aMCIs) and determine the association between the performance of the gait function and cognition.Methodology: In this study, we enrolled 38 patients with aMCI and 30 cognitively normal individuals normal controls (NC). Neuropsychological assessments included tests of memory, executive function, language, and attention. Using […]
Published on October 22, 2019