Fast Science is bad for scientists and bad for science. Slow Science may actually help us to make faster progress, but how can we slow down? Here, I offer preliminary suggestions for how we can transition to a healthier and more sustainable research culture. Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, […]

In this paper, we evaluate the computational performance of the GEneral NEural SImulation System (GENESIS) for large scale simulations of neural networks. While many benchmark studies have been performed for large scale simulations with leaky integrate-and-fire neurons or neuronal models with only a few compartments, this work focuses on higher fidelity neuronal models represented by […]

Although lipopolysaccharides (LPS) have been used to establish animal models of memory loss akin to what is observed in Alzheimer’s disease (AD), the exact mechanisms involved have not been substantiated. In this study, we established an animal model of learning and memory impairment induced by LPS and explored the biological processes and pathways involved. Mice […]