Parkinson’s disease (PD), the main risk factor of which is age, is one of the most common neurodegenerative diseases, thus presenting a substantial burden on the health of affected individuals as well as an economic burden. Sirtuin 2 (SIRT2), a subtype in the family of sirtuins, belongs to class III histone deacetylases (HDACs). It is […]

Successive patterns of activation and deactivation in local areas of the brain indicate the mechanisms of information processing in the brain. It is possible that this process can be optimized by principles, such as the maximization of mutual information and the minimization of energy consumption. In the present paper, I showed evidence for this argument […]

“Practice makes perfect” is a principle widely applied when one is acquiring a new sensorimotor skill to cope with challenges from a new environment. In terms of oral healthcare, the traditional view holds that restoring decayed structures is one of the primary aims of treatment. This assumes that the patient’s oromotor functions would be recovered […]