The current longitudinal study examined factors (sex, physical function, response to novelty, ability to adapt to a shift in light/dark cycle, brain connectivity), which might predict the emergence of impaired memory during aging. Male and female Fisher 344 rats were tested at 6, 12, and 18 months of age. Impaired spatial memory developed in middle-age […]

It is widely recognized that within mammalian societies an individual may be simultaneously a leader of collective behavior and hold a position of high status. Drawing from a comparative perspective, we recently suggested that some leaders are of low status or emerge in egalitarian societies lacking dominance hierarchies [1]. Furthermore, we noted that some high-ranking […]

Purpose: Gliomas are the most common primary brain malignancies, with varying degrees of aggressiveness and prognosis. Understanding of tumor biology and intra-tumor heterogeneity is necessary for planning personalized therapy and predicting response to therapy. Accurate tumoral and intra-tumoral segmentation on MRI is the first step toward understanding the tumor biology through computational methods. The purpose […]