ObjectiveTo examine whether the influence of hypertension (HTN) status on longitudinal changes in brain glucose metabolism was modified by the apolipoprotein 4 (APOE4) status among older people with normal cognition.MethodsIn this study, we included 217 older individuals with normal cognition from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study. Participants were divided into the HTN and […]
Published on April 3, 2020
Identifying patients with mild cognitive impairment (MCI) who are at high risk of progressing to Alzheimer’s disease (AD) is crucial for early treatment of AD. However, it is difficult to predict the cognitive states of patients. This study developed an extreme learning machine (ELM)-based grading method to efficiently fuse multimodal data and predict MCI-to-AD conversion. […]
Published on April 2, 2020
Abstract A number of recent models of semantics combine linguistic information, derived from text corpora, and visual information, derived from image collections, demonstrating that the resulting multimodal models are better than either of their unimodal counterparts, in accounting for behavioral data. Empirical work on semantic processing has shown that emotion also plays an important role […]
Published on April 1, 2020