ObjectiveTo establish a clinically relevant mouse model of perioperative delirium.MethodsAged C57BL/6J mice were tested at baseline in the Y-maze novel arm preference, buried food, simple discrimination task of the attentional set-shifting test, and open field tests. They were subsequently randomized to insult (anesthesia, surgery, and Intensive Care Unit environment) or control group. Insult-exposed mice received […]

Humans are ultrasocial, yet, theories of cognition have often been occupied with the solitary mind. Over the past decade, an increasing volume of work has revealed how individual cognition is influenced by the presence of others. Not only do we rapidly identify others in our environment, but we also align our attention with their attention, […]

The Baldwin effect is a hypothetical process in which a learned response to environmental change evolves a genetic basis. Modelling has shown that the Baldwin effect offers a plausible and elegant explanation for the emergence of complex behavioural traits, but there is little direct empirical evidence for its occurrence. We highlight experimental evidence of the […]