Synapse loss occurs early in Alzheimer’s disease (AD) patients and animal models. Alterations at synaptic level are a major morphological correlate of the memory deficits and related symptoms of AD. Given the predominant roles of synaptic AMPA receptors (AMPARs) in excitatory synaptic transmission in the brain, changes in their dynamic regulation are also implicated in […]
Published on October 6, 2020
ObjectiveIn this study, we aimed to examine if patterns of CSF inflammatory markers are correlated with global cognition, episodic memory, hippocampal volume, and CSF AD-related pathologies among non-demented older people.MethodsWe included 217 non-demented older individuals, including 87 subjects with normal cognition (NC) and 130 subjects with mild cognitive impairment (MCI) from the Alzheimer’s Disease Neuroimaging […]
Published on October 6, 2020
Does language change what we perceive? Does speaking different languages cause us to perceive things differently? We review the behavioral and electrophysiological evidence for the influence of language on perception, with an emphasis on the visual modality. Effects of language on perception can be observed both in higher-level processes such as recognition and in lower-level […]
Published on October 2, 2020