The glucocorticoid (GC) hypothesis posits that effects of stress and dysregulated hypothalamic-pituitary-adrenal axis activity accumulate over the lifespan and contribute to impairment of neural function and cognition in advanced aging. The validity of the GC hypothesis is bolstered by a wealth of studies that investigate aging of the hippocampus and decline of associated mnemonic functions. […]

Socioeconomic disparities impact neurocognitive functions. Yet, despite decades of research, the relationship between socioeconomic disparities and social cognition (the mental processes that allow us to understand and interact with others) remains controversial. Fendinger and colleagues [1] examine evidence spanning from psychology to the neurosciences and conclude that lower social class is consistently associated with improved […]

Neuroscience has made significant strides over the past decade in moving from a largely closed science characterized by anemic data sharing, to a largely open science where the amount of publicly available neuroscience data has increased dramatically. While this increase is driven in significant part by large prospective data sharing studies, we are starting to […]