Month: March 2024

Impact of olfactory function on the trajectory of cognition, motor function, and quality of life in Parkinson’s disease

BackgroundOlfactory dysfunction in Parkinson’s disease (PD) is associated with more severe phenotypes, but trajectories of cognitive function, disease severity, and subdomains of quality-of-life measurements in patients with distinct olfactory profiles remain underexplored.ObjectiveTo analyze the influence of olfaction on trajectories of clinical parameters in patients with PD.DesignRetrospective cohort study.SubjectsFrom October 2016 to May 2021, the study […]

Published on March 4, 2024

miR-3940-5p reduces amyloid β production via selectively targeting PSEN1

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid beta (Aβ) in brain. Mounting evidence has revealed critical roles of microRNAs (miRNAs) in AD pathogenesis; however, the miRNAs directly targeting presenilin1 (PSEN1), which encodes the catalytic core subunit of γ-secretase that limits the production of Aβ from amyloid precursor protein […]

Published on March 4, 2024

The Leafy Green Most Vulnerable to E. Coli

Salad lovers, take note: Lettuce is more vulnerable to E. coli contamination than other leafy greens, researchers report. The physical composition of green leaf and romaine lettuce makes it a happy home for E. coli bacteria, particularly at room temperature, according to a… Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, Ph.D., […]

Published on March 4, 2024