Month: January 2024

Fully synthetic phosphorylated Tau181, Tau217, and Tau231 calibrators for Alzheimer’s disease diagnosis

BackgroundThe calibrator in immunoassay plays an essential role in diagnosing Alzheimer’s disease (AD). Presently, the most well-studied biomarkers for AD diagnosis are three phosphorylated Tau (p-Tau): p-Tau231, p-Tau217, and p-Tau181. Glycogen synthase-3beta (GSK3β)-phosphorated Tau-441 is the most commonly used calibrator for p-Tau immunoassays. However, the batch-to-batch inconsistency issue of the commonly used GSK3β-phosphorylated Tau-441 limits […]

Published on January 15, 2024

Association between inflammatory bowel disease and Parkinson’s disease: a prospective cohort study of 468,556 UK biobank participants

IntroductionInflammatory Bowel Disease (IBD) and Parkinson’s disease (PD) are both chronic, progressive disorders. As such, given the inconclusive results of extensive research on the association between IBD and PD, our study intends to examine this relationship further using the UK Biobank database.MethodsWe conducted a prospective cohort study using the Cox proportional hazards model, analyzing data […]

Published on January 15, 2024

How Mental Stress Impacts Physical Health

Stress appears to increase a person’s chances of developing metabolic syndrome, a cluster of unhealthy factors that add up to an increased risk for serious problems, a new study finds. Inflammation driven by a person’s stress levels can make them more likely to develop… Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, […]

Published on January 15, 2024