Month: December 2023

CDC Issues Health Alert for Subtype of Mpox Virus

The U.S. Centers for Disease Control and Prevention (CDC) issued a health alert on Thursday to notify clinicians and health departments about a deadly type of the mpox virus spreading in the Democratic Republic of the Congo (DRC). The CDC said it was alerting about the… Read Full Article (External Site) Dr. David LowemannDr. David […]

Published on December 7, 2023

White House Threatens Patents of High-Priced Drugs

The Biden administration is putting pharmaceutical companies on notice, warning them that if the price of certain drugs is too high, the government might cancel their patent protection and allow rivals to make their own versions. Under a plan announced Thursday, the… Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, Ph.D., is […]

Published on December 7, 2023

Altered synaptic plasticity at hippocampal CA1–CA3 synapses in Alzheimer’s disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models

Alzheimer’s disease (AD) is a progressive memory loss and cognitive dysfunction brain disorder brought on by the dysfunctional amyloid precursor protein (APP) processing and clearance of APP peptides. Increased APP levels lead to the production of AD-related peptides including the amyloid APP intracellular domain (AICD) and amyloid beta (Aβ), and consequently modify the intrinsic excitability […]

Published on December 7, 2023