Month: December 2023

Classification of cognitive impairment in older adults based on brain functional state measurement data via hierarchical clustering analysis

IntroductionCognitive impairment (CI) is a common degenerative condition in the older population. However, the current methods for assessing CI are not based on brain functional state, which leads to delayed diagnosis, limiting the initiatives towards achieving early interventions.MethodsA total of one hundred and forty-nine community-dwelling older adults were recruited. Montreal Cognitive Assessment (MoCA) and Mini-Mental […]

Published on December 15, 2023

Sex moderates the association between age and myelin water fraction in the cingulum and fornix among older adults without dementia

BackgroundDecreasing white matter integrity in limbic pathways including the fornix and cingulum have been reported in Alzheimer’s disease (AD), although underlying mechanisms and potential sex differences remain understudied. We therefore sought to explore sex as a moderator of the effect of age on myelin water fraction (MWF), a measure of myelin content, in older adults […]

Published on December 15, 2023

Complications and outcomes of hospitalizations for patients with and without Parkinson disease

ObjectiveTo examine complications and outcomes of hospitalizations for common indications for hospitalization among patients with Parkinson disease (PD).MethodsWe identified and selected the ten most common indications for hospitalization among individuals ≥65 years of age using principal diagnoses from the California State Inpatient Database, 2018–2020. Patients with comorbid PD were identified using secondary diagnosis codes and matched […]

Published on December 15, 2023