Month: November 2023

Development of a diagnostic and risk prediction model for Alzheimer’s disease through integration of single-cell and bulk transcriptomic analysis of glutamine metabolism

BackgroundIn this study, we present a novel system for quantifying glutamine metabolism (GM) to enhance the effectiveness of Alzheimer’s disease (AD) diagnosis and risk prediction.MethodsSingle-cell RNA sequencing (scRNA-seq) analysis was utilized to comprehensively assess the expression patterns of GM. The WGCNA algorithm was applied to investigate the most significant genes related to GM. Subsequently, three […]

Published on November 10, 2023

Predicting progression of white matter hyperintensity using coronary artery calcium score based on coronary CT angiography—feasibility and accuracy

ObjectiveCoronary artery disease (CAD) usually coexists with subclinical cerebrovascular diseases given the systematic nature of atherosclerosis. In this study, our objective was to predict the progression of white matter hyperintensity (WMH) and find its risk factors in CAD patients using the coronary artery calcium (CAC) score. We also investigated the relationship between the CAC score […]

Published on November 10, 2023

Obesity, Diabetes Linked to Pancreatic Cancer

Having high insulin levels may be more than tough to manage when you have diabetes: New research shows it also appears to raise the risk of pancreatic cancer. In the study, scientists found excessive insulin levels overstimulated pancreatic acinar cells, which produce… Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, Ph.D., is […]

Published on November 10, 2023