The cognitive (lateral) hypothalamus

Published on September 26, 2023

Imagine the hypothalamus as a master switchboard in your brain, controlling not only basic functions like hunger and thirst, but also determining what you learn and remember. While it was previously believed that the lateral hypothalamus only regulated feeding behaviors, recent research has shown that it plays a critical role in learning about food-related cues. In fact, the lateral hypothalamus can influence your behavior towards or away from important events based on associations with food. This fascinating discovery adds a new layer of complexity to understanding how our brain processes information and adapts to the environment. Disorders like addiction and schizophrenia, which involve disruptions in this delicate balance, may be impacted by abnormal hypothalamic function. This highlights the importance of studying this intricate brain region to uncover new insights into learning and behavior. Delve deeper into the research to unravel the mysteries of the cognitive hypothalamus!

Despite the physiological complexity of the hypothalamus, its role is typically restricted to initiation or cessation of innate behaviors. For example, theories of lateral hypothalamus argue that it is a switch to turn feeding ‘on’ and ‘off’ as dictated by higher-order structures that render when feeding is appropriate. However, recent data demonstrate that the lateral hypothalamus is critical for learning about food-related cues. Furthermore, the lateral hypothalamus opposes learning about information that is neutral or distal to food. This reveals a unique arbitrator of learning capable of shifting behavior toward or away from important events. This has relevance for disorders characterized by changes in this balance, including addiction and schizophrenia. Generally, this suggests that hypothalamic function may be more complex than increasing or decreasing innate behaviors.

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