Month: July 2023

Keep Your Pets Safe in the Heat

It’s getting hot out there! Just like we humans need to take precautions in the scorching heat, our furry friends also need some special care during the summer months. AAA Living advises that when heading out with your pets for summer activities like a day at the beach or a hike in the wilderness, it’s […]

Published on July 5, 2023

O-GlcNAcylation regulates extracellular signal-regulated kinase (ERK) activation in Alzheimer’s disease

IntroductionAberrant activation of Extracellular Signal-Regulated Kinase (ERK) signaling is associated with Alzheimer’s disease (AD) pathogenesis. For example, enhanced ERK signal activation mediated by Apolipoprotein E4 (APOE4), which is a critical genetic risk factor for AD, increases the transcription of amyloid precursor protein (APP). We hypothesize that O-linked N-acetylglucosamine (O-GlcNAc) regulates the phosphorylation and activation of […]

Published on July 4, 2023