Month: July 2023

Empirical mode decomposition of local field potential data from optogenetic experiments

IntroductionThis study investigated the effects of cocaine administration and parvalbumin-type interneuron stimulation on local field potentials (LFPs) recorded in vivo from the medial prefrontal cortex (mPFC) of six mice using optogenetic tools.MethodsThe local network was subject to a brief 10 ms laser pulse, and the response was recorded for 2 s over 100 trials for […]

Published on July 5, 2023

Cerebrospinal fluid microRNAs as potential biomarkers in Alzheimer’s disease

Alzheimer’s disease (AD) is the leading form of dementia worldwide, but its early detection and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous RNA molecules that regulate mRNA expression. Recent evidence suggests miRNAs play an important role in the five major hallmarks of AD pathophysiology: amyloidogenesis, tauopathy, neuroinflammation, synaptic dysfunction, and […]

Published on July 5, 2023

A Bright Smile for a Bright Mind

Just like regular brushing keeps your pearly whites healthy, it turns out that taking good care of your teeth may also benefit your brain! A recent study suggests a link between gum disease, tooth loss, and brain health. Specifically, researchers found that individuals with gum disease and tooth loss had smaller hippocampi, the part of […]

Published on July 5, 2023