The Impact of Waist-to-Calf Ratio on Cognitive Function in Older Adults

Published on April 17, 2023

Just as a tight waistband on pants can restrict your movement and make you feel uncomfortable, a high waist-to-calf ratio (WCR) can have negative effects on the cognitive function of older adults. In this study, researchers wanted to understand the link between WCR and cognitive function, as well as the potential mediating factors involved. The results showed that a high WCR was associated with poorer cognitive function. Furthermore, physical performance and social activity were found to partially mediate this relationship. This means that engaging in regular physical activity and maintaining an active social life may help counteract the negative impact of a high WCR on cognitive function. The findings highlight the importance of multidimensional interventions aimed at improving physical, social, and cognitive well-being in older adults with higher WCR. To learn more about this fascinating study and its implications for healthy aging, check out the full article!

BackgroundIn light of the potentially detrimental effects of central fat and decreased muscle mass on cognitive function, it would be beneficial to learn more about the mediating mechanisms underpinning the association between the two. The purpose of this study is to determine the association between waist-to-calf circumstance ratio (WCR) and cognitive function, as well as to investigate whether physical performance and social activity mediate the relationship between WCR and cognitive function among older Chinese adults.MethodsAn analysis of 9,652 older Chinese adults was conducted during the 2018 wave of the Chinese Longitudinal Health Longevity Survey (CLHLS). The Mini-Mental State Examination (MMSE) and a self-reported scale were used to measure cognitive function, physical performance, and social activity, respectively. Multiple linear regression and mediation analyses were conducted.ResultsThe findings suggest that a high WCR had a significant negative association with cognitive function (B = −0.535, 95% CI: −0.754, −0.317). Mediation analysis revealed that a high WCR influenced old adults’ cognitive function in three ways: first, through the partial mediating effect of physical performance (B = −0.270; 95% CI: −0.340, −0.203); second, through the partial mediating effect of social activity (B = −0.035; 95% CI: −0.055, −0.017); and third, through the serial mediating effects of physical performance and social activity (B = −0.021, 95% CI: −0.029, −0.015).ConclusionThe study results suggest the adverse impact of a high WCR on older adults’ cognitive function, and the possible mechanisms of physical performance and social activity by which the association takes place. Multidimensional health and social interventions aimed at improving physical, social, and cognitive functioning among older adults with sarcopenic obesity are recommended.

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