Month: March 2023

APOE ε4/ε4 and Fluid Biomarkers in Dementia

Imagine the human brain as a complex orchestra, with different instruments playing different tunes. In this study, scientists focused on one particular instrument called Apolipoprotein-E (APOE) ε4, known to be a risk factor for Alzheimer’s disease (AD). They explored the associations between APOE ε4/ε4 and fluid biomarkers in patients with dementia and AD. Using cutting-edge […]

Published on March 31, 2023

Gray Matter Swagger: How Hypoxia and Sleep Disturbance Tangle in OSA

Imagine you’re hosting a party, and you invite two guests who don’t get along well — Hypoxia and Sleep Disturbance. As the night progresses, you observe that Hypoxia runs amok, causing changes in various party spots like the living room, kitchen, and backyard. On the other hand, Sleep Disturbance seems to be playing more mischief […]

Published on March 31, 2023

Unlocking the Puzzle of Cognitive Impairment in Cerebral Small-Vessel Disease

Imagine a jigsaw puzzle that represents cognitive impairment in cerebral small-vessel disease (CSVD). In this puzzle, two key pieces are white matter hyperintensity volume (WMH) and total white matter (WM) volume. Researchers wanted to see how these puzzle pieces fit together and if they could help evaluate cognitive dysfunction in CSVD patients. By analyzing brain […]

Published on March 31, 2023